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When we made these updates, we also revised the language at 414.1385 more generally, including a change from 30 days to 15 days between notification and a response at 414.1385(a)(5), but we did not make corresponding changes to the QP Targeted Review at 414.1455

In such cases, the subject still technically has PD, but the quality of life of the subject is significantly improved because the progression of symptoms is slowed, or even stopped (arrested) at an earlier stage than would be possible without administration of the HGF mimic(s), e.g

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