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When applied via injections, GHK-Cu may exert systemic effects related to DNA repair, healing of wounds, lung tissue repair, angiogenesis, and nerve outgrowth [4]

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Importantly, folate deficiency should not be treated in isolation if B12 deficiency is suspected, as this can precipitate neurological complications

In the physiological state, it is localized in the cell cytosol and is regulated by a variety of protein translational modifications (PTMs) to adapt to different cellular environments, such as phosphorylation, ubiquitination, S-nitrosylation, palmitoylation, and SUMOylation (Jin et al., 2021)