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Description

Semaglutide Semaglutide is a GLP-1based peptide that mimics a naturally occurring hormone involved in hunger and satiety

[DOI] [PubMed] [Google Scholar] 91

GLP-1 receptor agonists have transformed the management of type 2 diabetes and obesity, but their mechanism of delaying gastric emptying presents important clinical considerations

However, gene duplication would mean an increase in gene dosage, which would likely be deleterious as insulin release and glucose tolerance is sensitive to GLP-1 dosage 38,39