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Interestingly, TMA and TMAO production in the BB-supplemented mice showed no association with bacteria from the Bacteroides or Proteobacteria phyla, taxa that co-associated with plasma BB levels in L -carnitine fed mice (Table S2)

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They involve coordinated communication between: Pancreatic hormones Gut signaling pathways Brainstem regions Hypothalamic circuits Endocrine feedback systems Peripheral metabolic tissues From this perspective, cagrilintide is studied as a peptide that helps researchers understand how the body sends, receives, and interprets metabolic signals related to food intake and energy balance