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Review Methodology This review was prepared using publicly available information from leviapatch.com, published independent research on the ingredient categories the brand names, and a review of the current competitive landscape in the GLP-1 patch and berberine patch category

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Importantly, the effect of GLP-1 on alcohol intake may be driven locally by mesolimbic VTA GLP-1R activation, since acute intra-VTA injection of GLP-1 or EX4 reduces overnight alcohol consumption by nearly 30%, (Shirazi et al., 2013)