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Common side effects across all three include: Nausea Vomiting Diarrhea Constipation Bloating Headache Fatigue Wegovy and Ozempic Longer-acting semaglutide formulas often have fewer daily fluctuations in side effects May cause stronger nausea during the titration phase Once-weekly dosing improves adherence Saxenda Daily injections may result in more consistent but milder side effects Shorter-acting compounds may reduce long-term discomfort for sensitive users Side effects typically peak during the initial dose increases and improve over time

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