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In contrast, -mercaptoethanol inhibits erastin-induced ferroptosis by increasing the intracellular concentration of cystine (Takahashi et al., 2002)

Modifying Biosynthetic Pathways to Generate New Compounds The concept of combinatorial biosynthesis was first demonstrated in 1985, wherein Hopwood and coworkers explored the possibility of hybrid antibiotics via interchanging biosynthetic genes from related pathways found in different species