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Nrf2 activators, such as sulforaphane, have shown potential in preventing cataract formation in human lens epithelial cells under oxidative stress conditions

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Lipid peroxidation induces Deoxyribonucleic Acid (DNA) damage response, further activating NF-B to promote macrophage polarization toward the M1 phenotype [70]

These results demonstrate that, whereas carnitine can acquired from the diet, and dietary carnitine supplementation is correlated to increased fatty acid -oxidation capacity, de novo carnitine synthesis is critical to the process that dictate cellular fuel choices under different physiological conditions