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Autonomic adaptations mediate the effect of hydration on brain functioning and mood: Evidence from two randomized controlled trials

This treatment regimen focusing on the metabolism is fundamentally very different from the most common treatment rationales of depression, which are generally based on the use of antidepressants stimulating monoaminergic transmission 5

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Measuring biomarkers like fasting insulin, C-peptide, and inflammatory markers (hsCRP) can provide context for whether your metabolic profile aligns with conditions where prescription GLP-1 therapy has the strongest clinical evidence