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The choice of the Upper Horehronie case study area is based on previous knowledge and also on research that has been carried out in this area

Philippot G, Forsberg E, Tahan C, Viberg H, Fredrikson R

Atherosclerosis represents a state of intense oxidative stress characterized by vascular wall lipid and protein oxidation that contributes to chronic inflammation within the arterial wall, in which CRP is a major player (Figure 7)

03 Antioxidant Defense (Neutralizing Radicals) : Copper ions activate SOD and catalase, reducing oxidative stress and preventing structural protein degradation