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This mechanism remains controversial in explaining the physiologic decreases in weight loss seen in patients [150]

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Some studies have reported that knockdown of GLP-1R in ARC POMC neurons didnt alter body weight or composition, food intake, and energy expenditure, nor did it significantly alter the reduction of food intake by intraperitoneal (i.p.) exendin-4 [80]

Research the two cited from Cornell and Numerator showed GLP-1 users are buying more yogurt, meat snacks, candy, fruit and deli items and fewer salty snacks, sweet bakery items, eggs, vegetables and cheese