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The relative amounts of each form determine the cellular redox status (GSH/GSSG ratio) which is often used as a marker of antioxidative capacity of cells [2]

Conclusion In conclusion, our findings demonstrate that ROS regulate GSK3 dephosphorylation via the PI3K/Akt pathway, which in turn activates IP3R on the ER membrane to induce the release Ca 2+ into the cytoplasm

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