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The recommended approach is to take your last Wegovy dose, wait approximately 7 days, then start Retatrutide at the lowest dose (2 mg) and follow the standard escalation schedule

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Increasing fatty acid and ketone metabolism after a ketogenic diet also attenuated reductions in ATP, NAD, mitochondrial fragmentation, and myelination in a murine diffuse axonal injury model, while treatment with ketone bodies reduced neuronal/myelin damage induced by glucose deprivation in vitro [96]