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Chirumbolo S, Bjrklund G (2017) PERM hypothesis: the fundamental machinery able to elucidate the role of xenobiotics and hormesis in cell survival and homeostasis

108 A meta-analysis of findings from four randomized controlled trials found tryptophan, at doses of 1 gram or more nightly, was particularly effective at improving indicators of sleep maintenance, such as decreasing wakefulness after sleep onset and increasing sleep efficiency

Switching between GLP-1 medications needs care because doses are not directly interchangeable

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