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Arteriosclerosis, thrombosis and vascular biology 24, 22192226 (2004)
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Acetyl form crosses the blood-brain barrier supports both metabolic (fat oxidation) and cognitive (mental energy, alertness) pathways
In a randomized, double-blind, placebo-controlled trial in 2,919 participants (65 years) with elevated blood concentrations of homocysteine, supplementation with vitamin B 12 (500 g/day) and folic acid (400 g/day) for two years did not decrease the risk of osteoporotic fracture despite reductions in homocysteine (120, 121)
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