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3-6 Months: Maximum Benefits The 3-6 month period generally brings the most substantial results: Clinical trials show that patients lost 10-15% of their initial body weight on average Many patients report improved energy levels and mobility Health markers like blood pressure and blood sugar often show significant improvement Body composition changes become more apparent Physical activity typically becomes easier and more enjoyable During this period, the combined effects of weight loss, improved metabolic health and established healthy habits often create momentum that helps maintain long-term success

While these effects do not cause extra water loss through your kidneys or skin, they might alter daily habits, which could affect how hydrated you are

Phentermine is the opposite on this point: it reaches its peak concentration within a few hours and clears quickly, which fits its role as a short-term push

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