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doi:10.1111/j.1365-2036.2005.02673.x Chojnacki C, Walecka-Kapica E, Lokiec K, et al

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We found that adult-onset hypothyroidism can lead to ovarian dysfunction in rats, affecting the synthesis of sex hormones and ovulation, which may be caused by the increase apoptosis of granulosa cells in antral follicles and induce oxidative stress in oocytes

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