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Vildagliptin did not affect fat mass or food intake over 11 days of treatment (data not shown)

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Nevertheless, in addition to increasing the expression of genes involved in mitochondrial -oxidation, cooperation can also occur between mitochondria and peroxisomes as an adaptive mechanism to facilitate -oxidation in mammals ( Reference Van den Branden and Vamecq 57 , Reference Mannaerts, Debeer and Thomas 58 )