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Dose-Response Studies: Further studies may be required to determine the optimal dosing of CT-388 that balances efficacy and safety

Mittal says

04Dose Timing, Injection Sites, and Medication-Level Context MeAgain shows your current dose, the countdown to the next shot or pill, an injection site map that remembers where you injected last, and a medication-level chart that helps you understand the rhythm of the week

The absence of published bioavailability studies, coupled with theoretical limitations, suggests that berberine patches are unlikely to deliver therapeutically relevant amounts of the compound into systemic circulation