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After several years of research on biological therapies and small molecules to target inflammation, we need a different strategy to further get more insights into mechanisms underlying rheumatoid arthritis pathogenesis and identify potential new treatments, as a significant proportion of patients are partial responders

It is also important to consider the purity of the supplement

The research reported herein received funding from the European Research Council under Grant Agreement 323646 for a project entitled Chemical Youth ( In the review and decision process, the editor of AE , Niko Besnier, was seconded by Associate Editor Paige West because of his conflict of interest with the first author

Arch Toxicol 87, 155165, doi: 10.1007/s00204-012-0924-1 (2013)