whats the difference in tirzepatide and semaglutide vs Semaglutide: Which Weight Loss Drug Is Best Compounded Semaglutide vs. Compounded Tirzepatide:

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At a glance Most common cause / nausea and vomiting from GLP-1 GI side effects reducing fluid intake and increasing fluid loss Incidence of nausea (semaglutide 2.4 mg) / approximately 44% of participants in the STEP-1 trial reported nausea Incidence of vomiting (semaglutide 2.4 mg) / approximately 24% in STEP-1, the primary driver of acute fluid loss Incidence of diarrhea (semaglutide 2.4 mg) / approximately 30% in STEP-1, contributing to electrolyte depletion First-line treatment / oral rehydration with electrolytes

Researchers believe this may be due to how GLP-1 affects the gut by: Slowing motility Modulating nerve signaling Possibly reducing visceral hypersensitivity (pain response) There is also some early evidence that GLP-1 medications may reduce overall IBS symptom severity and medication use, although more long-term data is needed 6