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Key Takeaways Tirzepatide can accelerate weight loss, but prolonged calorie deficits can lead to muscle loss if protein intake and resistance training are not prioritized
The species studied included Sprague-Dawley rats, CD-1 mice, Beagle dogs, and cynomologus monkeys treated with-naphthoflavone or phenobarbital (all species), isoniazid (rat), pyrasole (monkey), dexamethasone (rat, mouse, monkey), rifampin (dog), or clofibric acid (rat, mouse, dog)
Insulin levels drop, which is metabolically beneficial but also affects insulin-like growth factor (IGF-1), a hormone that directly stimulates hair follicle growth
