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The pituitary gland, dangling from the bottom of our brain, secretes growth hormone in pulses, and this secretion is regulated by two main hormones: somatostatin blocks its release, while growth hormone-releasing hormone (or GHRH), as its name implies, encourages it

Pavel reported that ARBs prevent the response of the HPA axis to isolate stress and reduce the expression of CRH receptors and benzodiazepine receptors, demonstrating that ARBs exert powerful anti-anxiety properties by downregulating CRH receptor type and benzodiazepine receptors in stress models (151, 152)

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