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10.1021/ja908372b

The evidence consistently identifies several factors that increase risk further: Higher doses (the weight-loss doses of semaglutide and tirzepatide carry higher risk than the lower diabetic doses) Longer duration of treatment Faster rate of weight loss Pre-existing gallstones even asymptomatic ones found on a previous scan Female sex, age over 40, and family history of gallstones (the standard baseline risk factors, amplified by GLP-1 therapy) If several of these apply to you, the risk-benefit balance of your treatment plan is worth a structured discussion

Health disparities across racial and income lines make access to effective weight loss treatment a public health priority here

These ancient grains may have a place in a modern healthy diet, even, if not especially, if you have acid reflux or gastroesophageal reflux (GERD)