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We found that their risk of retained gastric contents was lower than the patients who had an upper endoscopy and did not take GLP-1RAs. Therefore, she noted, although GLP-1RAs may increase the risk for retained gastric contents, a clear liquid diet prior to a procedure may be protective of developing that complication or adverse event and is more important than holding the medication. We feel that the 2023 American Society of Anesthesiology recommendations need to be updated, Popov told Healio

The most commonly-reported side effects of GLP-1 pills are consistent with GLP-1 injections and include gastrointestinal issues such as nausea, vomiting and diarrhea, according to the trials

For anecdotal human evidence, high-profile users like Andrew Huberman have reported using BPC-157 for vertebral compression pain with positive results

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