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Anti-inflammatory effects of aloxistatin were further confirmed by reduced NFB activity in reporter cells and inhibited HLA-DR expression in human iPSC-derived macrophages

Potential benefits include: Appetite control and reduced caloric intake Improved blood sugar regulation Weight loss that supports overall metabolic health An alternative for patients unable or unwilling to use injections These medications may be particularly helpful for patients in the early stages of weight management or those who need medical support but are not ready or eligible for surgery

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doi: 10.1016/j.jdermsci.2009.08.003 39 Le PooleICvan den WijngaardRMWesterhofWVerkruisenRPDutrieuxRPDingemansKPet al