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Making it a potential future treatment for irritable bowel disease and inflammatory skin conditions like eczema and psoriasis

Conclusion: direct IV NAD+ has a real biological effect , although the mechanism is more complex than simple replenishment of the NAD+ pool (via metabolites)

In murine models, fluoxetine, escitalopram, venlafaxine, duloxetine and desipramine showed to alter gut microbiota composition, mainly reducing Ruminococcus, Adlercreutzia and an unclassified Alphaproteobacteria [263]