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Most non disease-specific guidelines suggest a daily or alternate day dose of 1000 g of intramuscularly B12 for 2 weeks and then a transition to a monthly regimen (Kramarz et al

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Older adults are at a higher risk for B12 deficiency for a number of reasons: Digestive issues that interfere with absorption Reduced food intake Dental issues that discourage meat consumption Disturbances to the gut biome Excess alcohol consumption Reduced stomach acid production that lowers absorption Reduced consumption and absorption of B12 can lead to neurological disorders, cognitive impairment and a number of other issues that accelerate aging and reduce overall quality of life