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Sales were slow, but grew steadily until American Spirit smokes became trendy

As a direct consequence of a reduction in exposure to carcinogenic toxicants, switching to a cMRTP use should also lead to a significant reduction in urinary genotoxicity (a biomarker of total genotoxic exposure) compared with continued smoking and approach the urinary genotoxicity observed upon smoking abstinence [37]

"You've come a long, long way," said the voiceover, as Hamel strutted away from the camera and into history

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