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and (ii) proliferative astrogliosis, which is anisomorphic with loss of domain, substantial structural reorganisation and can either be diffuse or can result in the formation of new compact limitans borders around overt fibrotic tissue lesions (Fig

Glutathione plays a crucial role in protecting cells from oxidative damage by interacting with vitamin C 31 and vitamin E 32 , participating in cellular metabolism 33 , and reducing cytotoxic effects 34