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The standard care for tendon, ligament, muscle, and bone injuries remains the foundation, and its a foundation built on decades of solid evidence: Conservative treatment : Rest, physical therapy, progressive loading, anti-inflammatory management, and activity modification remain first-line approaches for most musculoskeletal injuries

Activation of these receptors shifts immune cells toward an anti-inflammatory phenotype

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The median estimates from the bootstrap analysis were similar to the final PK parameter estimates, and the data fitting was reasonable as shown in the visual predictive check plots (Figure 4)