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With no head-to-head study, comparing the two requires stitching together trials that differ in population, comparator, endpoint, and duration a chain with several weak links

Currently, genetic deficiencies have been reported for five of the enzymes in the cycle: -glutamylcysteine synthetase, GSS, -glutamyl transpeptidase, 5-oxoprolinase, and dipeptidase (Figure 1)

In addition, the T2* changes correlated with reductions in ventricular volumes and hypertrophy and with increases in the EF and peak oxygen consumption

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