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Such tools may ultimately enable patient stratification based on plaque biology rather than traditional risk markers alone

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Interestingly, although DAF-16 is similarly activated in both glp-1(-) and fem-3(-) mutants, glp-1(-) shows a greater lifespan extension compared to fem-3(-) , again indicating that whereas DAF-16 is important, other factors are also likely to be key in modulating longevity in response to sterility 6,14,15,16,66

Furthermore, when compared to low-grade brain tumors, high-grade brain tumors exhibited a significant increase in lipid peroxidation along with a reduction in GSH (171)