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32 Metabolic-bariatric surgery has become remarkably safe, with 30-day mortality rates of 0.1% for laparoscopic sleeve gastrectomy and 0.2% for Roux-en-Y gastric bypass

Fielding R., Riede L., Lugo JP, Bellamine A

The fact that sKlotho was detected in urine indicates that renal epithelial cells were involved in Klotho metabolism because Klotho is too large to pass through the glomerular barrier (Hu et al., 2010)