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Rights and permissions About this article Cite this article Unlocking the broad health benefits and risks of GLP-1 receptor agonist drugs

Changes in facial muscle may contribute to a more angular or less supported appearance, although the degree varies among individuals

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More specifically speaking, GLP-1 receptor activation facilitates the presynaptic release of GABA into RGCs via the Gs/cAMP/PKA/Phospholipase C (PLC)/IP3/Ca2+/CaM signaling pathway, ultimately increasing the GABAergic miniature inhibitory postsynaptic currents (m-IPSCs) frequency and contrast sensitivity (Shao et al., 2024)