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Lancet (2014) 384:134957

Improving Adherence and Accessibility of GLP-1 Therapies in Adolescents Despite their benefits, adherence challenges remain a major concern, particularly among adolescents who may struggle with long-term commitment to injectable medications

In the meta-analysis of 3 studies 20,28,32 which compared a GLP-1-based therapy against a comparator, GLP-1-based therapies were found to increase % FMD non-significantly (mean difference [95% CI] in the changes from baseline: 1.65 [0.89, 4.18] %

Every individual person has unique needs and goals and the dose they need to achieve and maintain those goals is also unique