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I posted a poll on Twitter that asked learners/users you would replace vitamin B 12 in a patient with pernicious anemia, focusing on the choice between intramuscular (IM) and oral (PO) routes

These results suggest that the interaction between G3BP and ASPLs UBX+ region enhances G3BP condensation, alters the material properties of the SG condensate, and stabilizes the interaction of G3BP with other SG constituents, ultimately reducing the exchange rate between SG-localized G3BP with cytosolic G3BP and promoting SG formation

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In particular, Bcl-2 and Bcl-xL inhibit apoptosis by maintaining mitochondrial membrane integrity whereas Bax and Bak facilitate apoptosis by initiating the loss of outer mitochondrial integrity [21]