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At the highest dose, clinical trial patients lost about 10 pounds over a 9-month period - so while its not approved for weight loss, it may still have some weight-related benefits

Possible side effects include nausea, diarrhea, upset stomach, and flatulence

These bureaucratic hurdles mean many eligible patients abandon treatment pursuit entirely rather than navigate appeal processes

81 This observation, building on previous work in cancer biology, has led to the general concept of copper signaling 80 and metalloallostery 82 where variations in intracellular or organellar Cu bioavailability, mediated by Cu-specific transporters that transport copper across membranes, 83 regulates enzyme activity and signal transduction via as yet largely unknown mechanisms