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The gut-brain axis, gut-immune axis, and gut-skin axis all suggest that improving intestinal health can produce cascading improvements throughout the body

Clinical studies have demonstrated that Tirzepatide can lead to significant weight loss compared to placebo

Glucagon-like peptide 1 exerts its metabolic effects by activating the GLP-1 receptor, which is widely expressed in the GI tract, pancreas, and CNS (41, 42)

TJ complexes are primarily composed of transmembrane proteins including occludins, junctional adhesion molecules, and claudin family members that function collectively to form pores with selective permeability to ions and molecules (Brenchley and Douek 2012