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Cassidy lived 9 years post-diagnosis

Medical Evaluation Investigate potential medical contributors to weight loss resistance: Thyroid function: Check TSH if not recently assessed, as hypothyroidism impairs weight loss Medications: Review for weight-promoting drugs (antipsychotics, certain antidepressants, corticosteroids) Sleep disorders: Screen for sleep apnea and insufficient sleep, both associated with weight loss resistance Stress and cortisol: Chronic stress elevates cortisol, promoting central adiposity and metabolic dysfunction Dose Optimization If patients have not reached the maximum tolerated dose, consider further titration according to FDA labeling

Concretamente est contraindicado en embarazadas (en exceso puede afectar al desarrollo neuronal e incluso producir dependencia) y lactantes, adems de en aquellas personas con insuficiencias renales o hepticas

Eradication of malaria is challenging due to the development of resistance against the drugs