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Specific situations requiring GP discussion: Inadequate glycaemic control: If blood glucose remains elevated despite four weeks at current dose Hypoglycaemia: Particularly if taking sulfonylureas or insulin concurrently (dose adjustments of these medications may be needed) Significant weight loss: Unintended excessive weight reduction Planned surgery or acute illness: Temporary treatment modifications may be necessary Pregnancy planning: Ozempic should be discontinued at least two months before conception New medications: Potential drug interactions require review Visual changes: Especially if you have pre-existing diabetic retinopathy Symptoms of gallbladder disease: Persistent right upper abdominal pain, fever, or jaundice Never adjust your Ozempic dose independently or discontinue treatment without medical guidance