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Cobalamin deficiency can lead to neurological manifestations such as progressive axonal demyelination, impaired peripheral and sensory nerve function, areflexia, loss of proprioception and vibration sensitivity, and subacute combined spinal cord degeneration (, )

Table 2: Synthesis Yield Optimization Key advantages of this method include solvent recyclability (acetate/acetone recovery) and catalyst-free purification

Drugs that can damage the liver and cause heat-related damage include: Corticosteroids, synthetic hormones, NSAIDs Statins and cholesterol-lowering meds Acetaminophen (paracetamol) Antibiotics, antimalarials, antifungals, and antivirals Opioids Chemotherapy drugs (e.g., busulfan) Vitamin A (retinoids) Cocaine and methamphetamines Drug-induced liver injury (DILI) is a major cause of liver failure and is linked to abnormal globulin levels

Remember that individual responses can vary, and it may take multiple sessions to see noticeable changes in skin tone