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Because periodic blood monitoring is required for many anticoagulants, such as INR, PT, or aPPT, the healthcare provider must emphasize the importance of completing these labs and attending their scheduled visits (15,11)

In contrast, the Sal A methylation can be inhibited because of the diminished SAM and consequent hypomethylation in hyperlipidemic rats (Table 2)

The one honest exception: TB-500 works partly by mass-action, so a higher local concentration in the brief window before it disperses is at least plausible

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