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Enhanced trophic factor secretion by mesenchymal stem/stromal cells with Glycine-Histidine-Lysine (GHK)-modified alginate hydrogels

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These findings suggest that intranasal GHKCu has the potential to attenuate features of AD, including cognitive decline, amyloid plaque accumulation, and neuroinflammation, and provide the rationale for further studies in aging mice, for example using an AAV vector containing sequences of A42 and mutant tau [48]

Return to quiescence of mouse neural stem cells by degradation of a proactivation protein