effects of semaglutide What Should I Expect During the First Week GLP-1 Exploring beyond numeric weight loss:

Clinical evidence from the SURMOUNT trials demonstrated continued weight loss and maintenance through 72 weeks of treatment, with participants who discontinued therapy experiencing significant weight regain

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According to NICE, Wegovy should only be used within specialist weight management services, generally for people with a BMI 35 kg/m (lower thresholds may apply for some minority ethnic groups) with at least one weight-related comorbidity, and for a maximum duration of 2 years