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Inositol benefits for PCOS include improved insulin sensitivity 19 , fertility and pregnancy outcomes, metabolic health, and inflammation
Who Is Generally Excluded FDA labels list contraindications and precautions that typically rule out or require caution with GLP-1 therapy: Personal or family history of medullary thyroid carcinoma Multiple endocrine neoplasia syndrome type 2 (MEN 2) Known hypersensitivity to the drug History of pancreatitis (caution, not absolute contraindication) Active gallbladder disease (caution) Severe gastroparesis or other significant GI motility disorders Pregnancy or planning pregnancy (discontinuation typically recommended) Type 1 diabetes (not studied for this indication) Additionally, patients with severe kidney or liver disease, those on certain medications that affect insulin or GI motility, and those with eating disorders should have careful evaluation

doi: 10.3389/fendo.2024.1330936 Received 31 October 2023 Accepted 02 January 2024 Published 06 February 2024 Volume 15 - 2024 Edited by Julianne Hall, Quinnipiac University, United States Reviewed by Eric Morris Bomberg, University of Minnesota, United States Michihiro Takahashi, Takahashi Psychiatric Clinic, Japan Updates Copyright 2024 Chen, Cai, Zou and Fu