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257 Due to these backbone modifications, PNAs show improved resistance to nuclease and protease digestion
Results are highly individual and can depend on factors such as dosage, diet, exercise frequency, age, and overall health status
The rising economic burden of Type 2 Diabetes is a major health concern globally
Some PK studies report an increased theoretical risk of toxicity with advancing age [62,63,64,65,66,67] due to prolongation of t 1/2 [62, 63], reduced paracetamol clearance [64, 67], increased paracetamol oxidation caused by a reduction in glucuronidation and sulphation capacity [65] or a reduction in liver volume [66]
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