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These models allow for transmigration studies as well as more precise measurements of TEER making them very useful in permeability studies and reduces the number of cells needed for the model [117]

Existing studies mostly focus on single pathways or cell types, lacking a comprehensive explanation of the systemic remodeling of immune-metabolic networks, especially the mechanisms of inter-organ metabolic-immune axes and metabolic crosstalk among different immune cell subsets remain unclear (Thenappan and Weir, 2024

metabolism) to make them suitable for elimination

You know, again, that's, that's why this is in the gray area, but I will, there's, like I said, there's part of me that wants to then after six weeks, go back and, and train like more than I had been and see if it makes a difference