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Scientists had to synthesize the 39-amino-acid peptide in quantities sufficient for clinical trials, formulate it for injection, and demonstrate safety and efficacy in thousands of patients

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Liver Tests In a pediatric clinical trial for weight reduction, increases in alanine aminotransferase (ALT) greater than or equal to 5 times the ULN were observed in 4 (3%) WEGOVY-treated patients compared with 0% of placebotreated patients

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