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Lancet (2019) 394:12130

These data suggested that the gut makes a hormone(s) that regulates insulin levels, and they came to be known as incretins which were defined by Creutzfeld as factors that i) are released from gut in response to carbohydrates, ii) stimulate insulin secretion, and iii) act only in the presence of high blood glucose (2)

GLP-1R (Abcam antibody, E), and PGP9.5 (F), staining in avulsion injury DRG, magnification x20

At a San Diego conference last year, I presented data from 403 bariatric patients showing that while outcomes were similar across income levels after a year, patients from the lowest socioeconomic areas showed significantly lower weight loss and follow-up rates after three years